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Upon ligand binding, the nanoparticle-receptor complex is internalized via clathrin-coated vesicles to be transported across the BBB and subsequently released by exocytosis into the brain parenchyma 119,120

It remained uncorrected for a decade

Yale J Biol Med 80(2):51 Xu R, Wang F, Yang H, Wang Z (2022) Action sites and clinical application of HIF-1 inhibitors

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